First in Europe: one of the most precise Mass Spectrometers in the world

A couple of months ago, the CRG-UPF Proteomics Unit at the PRBB – run by the Centre for Genomic Regulation (CRG) and the Pompeu Fabra University (UPF) – announced the installation of one of the most precise mass spectrometers in the world, marketed as Orbitrap Fusion Lumos, becoming the first place in Europe and the third in the world to have this tribrid instrument. You can read more about this innovative mass spectrometer – which can achieve simultaneous analysis and quantification of more than 10,000 proteins from ten different samples in a single day! – in a post entitled “The CRG Becomes the First European Centre to Have One … Continue reading First in Europe: one of the most precise Mass Spectrometers in the world

Recreating the images of the mind

On “Back to the future” day, October 21st, 2015, Luís Seoane, member of the Complex Systems Lab at the IBE (UPF-CSIC) led by Ricard Solé, wrote a blog post called “Images of the mind”. In it, he discusses how much technology has advanced in the last 30 years. Our present is not quite the ‘future’ of the characters of the film directed by Robert Zemeckis, produced by Steven Spielberg and starring Michael J. Fox. But we have gone a long way. In this post, Seoane focuses on Brain Computer Interfaces, which are bringing back motility and communication to injured patients, and on which he himself has worked prior … Continue reading Recreating the images of the mind

Europeans are becoming more aware of the city air around them

Guest post written by Tom Cole-Hunter, researcher at the CREAL. Photos by Raül Torán. In the months of September and October, the Centre for Research in Environmental Epidemiology (CREAL, an ISGlobal centre) collaborated with the Institute of Photonic Sciences (ICFO) as partners in the iSPEX-EU project. The essence of this project is to capitalize on large-scale, citizen contributions to science (‘citizen science’) such as observations of their environment with simple tools that compliment their existing way-of-life. CREAL, identified by ICFO as now prominent in local citizen science activities due to leading roles in projects such as CITI-SENSE, was approached to assist in the … Continue reading Europeans are becoming more aware of the city air around them

Challenging the model: transcription without the canonical histone marks

A guest post written by Silvia Perez Lluch, from Roderic Guigó’s laboratory at the CRG. You can find more about her career and work here. Transcription is a process that depends on many elements such as transcription factors, DNA methylation and chromatin structure. Histones are essential for the proper regulation of transcription, and the posttranslational modifications on their tails have been related both to activation (H3K4me3, H3K9ac and H3K36me3) and silencing (H3K27me3 and H3K9me3) of gene expression. Using the fruit fly as model organism, in our lab at the CRG and in collaboration with Montserrat Corominas’ lab in the Universitat de … Continue reading Challenging the model: transcription without the canonical histone marks